EMD-70562

Single-particle
2.8 Å
EMD-70562
3D View Gallery
Deposition: 09/05/2025
Map released: 10/12/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70562

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9okf summary report (pdf.gz) Map-9okf FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human SV2A in the apo state

EMD-70562

Single-particle
2.8 Å
EMD-70562
3D View Gallery
Deposition: 09/05/2025
Map released: 10/12/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human SV2A in the apo state
Fitted models: 9okf

Deposition Authors: Pidathala S , Dai Y , Lee CH
Structural pharmacology of SV2A reveals an allosteric modulation mechanism in the major facilitator superfamily.
Pidathala S , Chen X, Dai Y , Nguyen LN , Gorgulla C , Niu Y, Liu F , Lee CH
(2025) Nat Commun , 16 , 10748 - 10748
PUBMED: 41315229
DOI: doi:10.1038/s41467-025-65781-1
ISSN: 2041-1723