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EMD-70557

Helical reconstruction
2.92 Å
EMD-70557
3D View Gallery
Deposition: 09/05/2025
Map released: 24/12/2025
Last modified: 31/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70557
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9oka summary report (pdf.gz) Map and 9oka FULL report (pdf.gz)
EMICSS annotations (xml)

Cardiac lambda-6 light chain amyloid AL-224L single protofilament

EMD-70557

Helical reconstruction
2.92 Å
EMD-70557
3D View Gallery
Deposition: 09/05/2025
Map released: 24/12/2025
Last modified: 31/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cardiac tissue-derived immunoglobulin l6 light chain AL-224L
Fitted models: 9oka

Deposition Authors: Hicks CW, Gursky O, Huda N
Cryo-EM of cardiac AL-224L amyloid reveals shared structural motifs and mutation-induced differences in lambda 6 light chain fibrils.
Hicks CW, Prokaeva T, Spencer B, Jayaraman S, Huda N, Wong S, Chen H, Sanchorawala V, Lavatelli F, Gursky O
(2025) J Mol Biol , 169591 - 169591
PUBMED: 41389958
DOI: doi:10.1016/j.jmb.2025.169591
ISSN: 1089-8638
ASTM: JMOBAK