Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-70530
Tetrameric full-length HIV-1 integrase protein complex
EMD-70530
Single-particle6.92 Å
Deposition: 06/05/2025Map released: 25/06/2025
Last modified: 23/07/2025
Sample Organism:
HIV type 1,
HIV-1 06TG.HT008
Sample: Full-length tetrameric HIV-1 integrase
Deposition Authors: Jing T
,
Lyumkis D
,
Shan Z
Sample: Full-length tetrameric HIV-1 integrase
Deposition Authors: Jing T
,
Lyumkis D
,
Shan Z
Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding.
Jing T
,
Shan Z
,
Dinh T
,
Biswas A
,
Jang S,
Greenwood J,
Li M
,
Zhang Z,
Gray G,
Shin HJ,
Zhou B
,
Passos D,
Strutzenberg TS
,
Aiyer S
,
Andrade L
,
Zhang Y,
Li Z,
Craigie R
,
Engelman AN
,
Kvaratskhelia M
,
Lyumkis D
(2025) bioRxiv
,
Shan Z
,
Dinh T
,
Biswas A
,
Jang S,
Greenwood J,
Li M
,
Zhang Z,
Gray G,
Shin HJ,
Zhou B
,
Passos D,
Strutzenberg TS
,
Aiyer S
,
Andrade L
,
Zhang Y,
Li Z,
Craigie R
,
Engelman AN
,
Kvaratskhelia M
,
Lyumkis D
(2025) bioRxiv
Grant Support:
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI136680 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI146017 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI170855 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI039394 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI170791 (United States)
