EMD-70317

Single-particle
3.0 Å
EMD-70317
3D View Gallery
Deposition: 24/04/2025
Map released: 10/09/2025
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70317

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ocj summary report (pdf.gz) Map-9ocj FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Transporter associated with antigen processing (TAP) bound to the viral protein CPXV012 in the outward-facing open state

EMD-70317

Single-particle
3.0 Å
EMD-70317
3D View Gallery
Deposition: 24/04/2025
Map released: 10/09/2025
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Cowpox virus
Sample: Ternary complex of the heterodimer TAP1 and TAP2 bound to the viral inhibitor CPXV012.
Fitted models: 9ocj

Deposition Authors: Lee J, Manon V , Chen J
Structurally diverse viral inhibitors converge on a shared mechanism to stall the antigen transporter TAP.
Lee J, Manon V , Chen J
(2025) PNAS , 122 , e2516676122 - e2516676122
PUBMED: 40956880
DOI: doi:10.1073/pnas.2516676122
ISSN: 1091-6490
ASTM: PNASA6