EMD-70314

Single-particle
3.8 Å
EMD-70314 Deposition: 24/04/2025
Map released: 10/09/2025
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70314

Transporter associated with antigen processing (TAP) bound to the viral protein BNLF2a in the inward-facing state

EMD-70314

Single-particle
3.8 Å
EMD-70314 Deposition: 24/04/2025
Map released: 10/09/2025
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, human gammaherpesvirus 4
Sample: Ternary complex of the heterodimer TAP1 and TAP2 bound to the viral inhibitor BNLF2a
Fitted models: 9ocg

Deposition Authors: Lee J, Manon V , Chen J
Structurally diverse viral inhibitors converge on a shared mechanism to stall the antigen transporter TAP.
Lee J, Manon V , Chen J
(2025) PNAS , 122 , e2516676122 - e2516676122
PUBMED: 40956880
DOI: doi:10.1073/pnas.2516676122
ISSN: 1091-6490
ASTM: PNASA6