EMD-70084

Single-particle
1.9 Å
EMD-70084
3D View Gallery
Deposition: 07/04/2025
Map released: 04/03/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70084

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9o3w summary report (pdf.gz) Map-9o3w FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human 80S ribosome bound to IDB-001 stalled on MYC nascent chain

EMD-70084

Single-particle
1.9 Å
EMD-70084
3D View Gallery
Deposition: 07/04/2025
Map released: 04/03/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human 80S ribosome bound to IDB-001 stalled on MYC nascent chain
Fitted models: 9o3w

Deposition Authors: Sauer PV , Schuller AP , Hamann LG
Context-dependent translation inhibition as a cancer therapeutic modality.
Diamond PD, Sauer PV , Holm M, Swanson-Swett CJ, Ferguson L, Bratset NM , Wienker GW, Sim JS, Adams HK, Kenner L, Meyers M, Gygi D, Konst ZA, Bahmanyar SS, Hamann LG, Schuller AP
(2026) Nat Commun , 17
PUBMED: 41735331
DOI: doi:10.1038/s41467-026-69891-2
ISSN: 2041-1723
Grant Support: