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EMD-70078

Single-particle
2.28 Å
EMD-70078
3D View Gallery
Deposition: 07/04/2025
Map released: 12/11/2025
Last modified: 26/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70078
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9o3f summary report (pdf.gz) Map and 9o3f FULL report (pdf.gz)
EMICSS annotations (xml)

Plasmodium falciparum 20S proteasome bound to inhibitor 296

EMD-70078

Single-particle
2.28 Å
EMD-70078
3D View Gallery
Deposition: 07/04/2025
Map released: 12/11/2025
Last modified: 26/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Plasmodium falciparum 3D7
Sample: Plasmodium falciparum 20S proteasome bound with inhibitor 296
Fitted models: 9o3f

Deposition Authors: Han Y, Deng X, Ray S, Phillips M, Phillips M
Optimization of Species-Selective Reversible Proteasome Inhibitors for the Treatment of Malaria.
Gahalawat S, Ray S, Zhang X, Deng X, Han Y, Chen Z, Lawong A, Shackleford DM, Katneni K, Chen G, Li P, Ng A, Zhong L, Hu M, McInerney M, Wang W, Saunders J, Collins D, Jayaseelan J, Noack CL, C Maity B, De N, Laleu B, Campbell SF, Phillips MA, Charman SA, Ready JM
(2025) J Med Chem , 68 , 23485 - 23520
PUBMED: 41148577
DOI: doi:10.1021/acs.jmedchem.5c02394
ISSN: 0022-2623
ASTM: JMCMAR