EMD-69221

Single-particle
2.85 Å
EMD-69221
3D View Gallery
Deposition: 16/02/2026
Map released: 01/07/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-69221

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-23sr summary report (pdf.gz) Map-23sr FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of CDK2 in complex with CRBN/DDB1 and B11

EMD-69221

Single-particle
2.85 Å
EMD-69221
3D View Gallery
Deposition: 16/02/2026
Map released: 01/07/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: CDK2 in complex with CRBN/DDB1 and B11
Fitted models: 23sr

Deposition Authors: Li XZ, Jiang Y
Selective CDK2 Degradation via Noncanonical Recruitment.
Pei Y, Lin W, Li X, Meng Y, Yin Y, Pan B, Zhou L, Cao L, Cang Y, Jiang Y, Lu W, Meng Z
(2026) J Med Chem , 69 , 15996 - 16024
PUBMED: 42334090
DOI: doi:10.1021/acs.jmedchem.6c01264
ISSN: 0022-2623
ASTM: JMCMAR