EMD-66146

Single-particle
3.15 Å
EMD-66146
3D View Gallery
Deposition: 09/09/2025
Map released: 16/09/2026
Last modified: 16/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-66146

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9wpq summary report (pdf.gz) Map-9wpq FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

5-HT2AR bound to LSD in complex with mini-Gq and scFv16 obtained by cryo-electron microscopy (cryoEM)

EMD-66146

Single-particle
3.15 Å
EMD-66146
3D View Gallery
Deposition: 09/09/2025
Map released: 16/09/2026
Last modified: 16/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: 5-HT2AR bound to LSD in complex with mini-Gq and scFv16 obtained by cryo-electron microscopy (cryoEM)
Fitted models: 9wpq

Deposition Authors: Li H, Tang L, Zhang J, Meng B, Cao D, Chen Y, Yu J, Liu Z, Wang S, Cheng J

Structure-based design of subtype-selective psychedelic analogues
Li H, Tang J, Zhang J, Meng B, Cao D, Yu J, Liu Z, Wang S, Cheng J
To Be Published