EMD-66105
Co-transcriptional histone H3K36 methylation complex containing RNA polymerase II elongation complex, Set2, and the upstream nucleosome. (temp130, type A)
EMD-66105
Single-particle4.28 Å
Deposition: 03/09/2025Map released: 24/12/2025
Last modified: 04/03/2026
Sample Organism:
Komagataella phaffii (strain GS115 / ATCC 20864),
Homo sapiens,
synthetic construct
Sample: Co-transcriptional histone H3K36 methylation complex containing RNA polymerase II elongation complex, Set2, and the upstream nucleosome. (temp130, type A)
Fitted models: 9wmu
Deposition Authors: Kujirai T
,
Ehara H
,
Ito T
,
Henmi M
,
Sekine S,
Kurumizaka H
Sample: Co-transcriptional histone H3K36 methylation complex containing RNA polymerase II elongation complex, Set2, and the upstream nucleosome. (temp130, type A)
Fitted models: 9wmu
Deposition Authors: Kujirai T
,
Ehara H
,
Ito T
,
Henmi M
,
Sekine S,
Kurumizaka H
Structural basis of transcription-coupled H3K36 trimethylation by Set2 in coordination with FACT.
Kujirai T
,
Ehara H
,
Ito T
,
Henmi M
,
Oya E
,
Kobayashi T
,
Sekine SI
,
Kurumizaka H
(2026) Sci Adv , 12 , eaed1952 - eaed1952
,
Ehara H
,
Ito T
,
Henmi M
,
Oya E
,
Kobayashi T
,
Sekine SI
,
Kurumizaka H
(2026) Sci Adv , 12 , eaed1952 - eaed1952
Grant Support:
- Japan Agency for Medical Research and Development (AMED): JP24ama121009 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP20H05690 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP24H00062 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP20H03201 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP23K17392 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP22K15033 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP24H02328 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP23H05475 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP20H05906 (Japan)
- Japan Science and Technology: JPMJER1901 (Japan)
- Japan Science and Technology: JPMJCR24T3 (Japan)
- Other private: Daiichi Sankyo Foundation for Life Science
