EMD-65617

Single-particle
2.96 Å
EMD-65617
3D View Gallery
Deposition: 30/07/2025
Map released: 01/07/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65617

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9w43 summary report (pdf.gz) Map-9w43 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the complex of human PD-1 and a PD-1-directed antibody

EMD-65617

Single-particle
2.96 Å
EMD-65617
3D View Gallery
Deposition: 30/07/2025
Map released: 01/07/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: PD1-fab complex
Fitted models: 9w43

Deposition Authors: Jiang WB, Xu JL
Dual agonism and selective T-cell depletion activity of a PD-1-directed antibody for treating autoimmune diseases.
Jiang W, Li L, Xue W, He X, Chu X, Song L, Li X, Zhao R, Yuan X, Jin X, Fan L, Sun T, Zhu A, Zhou L, Gu F, Xu Q, Ma G, Wang S, Jin L, Xu JL
(2026) MABs , 18 , 2624881 - 2624881
PUBMED: 41640111
DOI: doi:10.1080/19420862.2026.2624881
ISSN: 1942-0870
Grant Support: