EMD-65385

Single-particle
2.66 Å
EMD-65385
3D View Gallery
Deposition: 16/07/2025
Map released: 14/01/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65385

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9vvo summary report (pdf.gz) Map-9vvo FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

cryo-EM structure of gastric proton pump bound to YK01

EMD-65385

Single-particle
2.66 Å
EMD-65385
3D View Gallery
Deposition: 16/07/2025
Map released: 14/01/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Sus scrofa
Sample: pig gastric proton pump alpha-beta complex
Fitted models: 9vvo

Deposition Authors: Saito H, Abe K
Design, synthesis, and structural analysis of an inhibitor of the gastric proton pump with a diaza-tricyclic skeleton.
Umekubo N , Hashizume A, Saito H, Kato S, Kanai C , Gopalasingam CC , Gerle C , Shigematsu H , Yoshimori A , Abe K , Yokoshima S
(2026) Org.Biomol.Chem. , 24 , 1000 - 1005
PUBMED: 41536160
DOI: doi:10.1039/d5ob01828e
ISSN: 1477-0539