EMD-65368

Single-particle
2.84 Å
EMD-65368 Deposition: 13/07/2025
Map released: 27/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65368

Cryo-EM structure of the Nipah virus RNA-dependent RNA polymerase complex bound to allosteric inhibitor ERDRP-0519

EMD-65368

Single-particle
2.84 Å
EMD-65368 Deposition: 13/07/2025
Map released: 27/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Henipavirus nipahense
Sample: Nipah virus RNA-dependent RNA polymerase complex bound to allosteric inhibitor ERDRP-0519
Fitted models: 9vum

Deposition Authors: Du T, Wang J, Wu S, Ru H
Structural insights into measles virus RNA synthesis regulation and pan-paramyxoviral polymerase inhibition by ERDRP-0519.
Du T, Wang J, Yang C, Xue R, Chen Y, Jie K, Zhang X, Zhang L, Song G, Zhang Q, Wu S, Ru H
(2026) PNAS , 123 , e2522978123 - e2522978123
PUBMED: 41941628
DOI: doi:10.1073/pnas.2522978123
ISSN: 1091-6490
ASTM: PNASA6