EMD-65225

Single-particle
3.47 Å
EMD-65225
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Deposition: 02/07/2025
Map released: 31/12/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65225
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9vor summary report (pdf.gz) Map and 9vor FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM Structure of Human GPR158 Bound to Nanobody Nb20

EMD-65225

Single-particle
3.47 Å
EMD-65225
3D View Gallery
Deposition: 02/07/2025
Map released: 31/12/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: GPR158 complexed with Nb20
Fitted models: 9vor

Deposition Authors: Laboute T, Zucca S, Sial M, Sharma M, Brunori G, Singh S, Singh A, Martemyanov K
Targeting mGlyR with nanobodies for depression
Laboute T, Zucca S, Sial OK, Sharma M, Brunori G, Singh S, Nageswar K, Peng H, Rader C, Becker JA, Le Merrer J, Singh AK, Martemyanov KA
(2026) Nat Commun , 17 , 831
DOI: doi:10.1038/s41467-026-68339-x
ISSN: 2041-1723