EMD-65160

Single-particle
3.01 Å
EMD-65160
3D View Gallery
Deposition: 25/06/2025
Map released: 07/01/2026
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65160

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9vlg summary report (pdf.gz) Map-9vlg FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of human alpha-2/delta-1 with crisugabalin

EMD-65160

Single-particle
3.01 Å
EMD-65160
3D View Gallery
Deposition: 25/06/2025
Map released: 07/01/2026
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Structure of human alpha-2/delta-1 with crisugabalin
Fitted models: 9vlg

Deposition Authors: Wang J , Chen Z, Gou X
Structural and Computational Insights into the Mechanism of the Superior Pharmacological Activity of Crisugabalin: A Third-Generation Cav alpha 2 delta 1 Ligand.
Chen Z, Gou X, Meng Q, Li H, Li Y , Shi Z, Li X, Wang J
(2026) J.Chem.Inf.Model. , 66 , 632 - 641
PUBMED: 41439594
DOI: doi:10.1021/acs.jcim.5c02583
ISSN: 1549-960X
Grant Support: