EMD-64869

Helical reconstruction
2.62 Å
EMD-64869
3D View Gallery
Deposition: 30/05/2025
Map released: 08/04/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-64869

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9v9c summary report (pdf.gz) Map-9v9c FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human TNFR1 DD filament

EMD-64869

Helical reconstruction
2.62 Å
EMD-64869
3D View Gallery
Deposition: 30/05/2025
Map released: 08/04/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: TNFR1 DD filament
Fitted models: 9v9c

Deposition Authors: Zhao K , Liu JP, Liu C , Yuan JY
Electric dipole moment drives the dynamics of the TNFR1 complex I signalosome.
Liu J , Zhao J , Gao J, Zhao K , Han Y , Yang J , Li Z , Ye J , Sun Z , Wang F, Liu X, Li Z , Ji S, Liu B, Liu C , Zhang Y , Yuan J , Chou JJ
(2026) Nature , 653 , 1196 - 1204
PUBMED: 41922760
DOI: doi:10.1038/s41586-026-10304-1
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: