EMD-64603
RNA polymerase II elongation complex stalled at SHL(-0.5) in the hexasome of the overlapping dinucleosome
EMD-64603
Single-particle3.74 Å
Deposition: 14/05/2025Map released: 01/07/2026
Last modified: 29/07/2026
Sample Organism:
Komagataella phaffii GS115,
Homo sapiens,
synthetic construct
Sample: RNA polymerase II elongation complex stalled at SHL(-0.5) in the hexasome of the overlapping dinucleosome
Fitted models: 9uxw
Deposition Authors: Chen Z, Ho C, Tanaka H, Kujirai T
,
Ogasawara M,
Ehara H ,
Sekine S,
Takizawa Y ,
Kurumizaka H
Sample: RNA polymerase II elongation complex stalled at SHL(-0.5) in the hexasome of the overlapping dinucleosome
Fitted models: 9uxw
Deposition Authors: Chen Z, Ho C, Tanaka H, Kujirai T
,
Ogasawara M,
Ehara H ,
Sekine S,
Takizawa Y ,
Kurumizaka H
Structural basis of asymmetric transcription through a composite nucleosome formed by a hexasome and an octasome.
Chen Z,
Ho CH,
Tanaka H,
Kujirai T ,
Ogasawara M,
Ehara H ,
Sekine SI ,
Takizawa Y ,
Kurumizaka H
(2026) Nat Struct Mol Biol , 33 , 1097 - 1104
,
Ogasawara M,
Ehara H ,
Sekine SI ,
Takizawa Y ,
Kurumizaka H
(2026) Nat Struct Mol Biol , 33 , 1097 - 1104
Grant Support:
- Japan Society for the Promotion of Science (JSPS): JP20H05690 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP25K18403 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP24H02319 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP24H00062 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP20H03201 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP23K17392 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP24H02328 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP23H05475 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP20H05906 (Japan)
- Japan Science and Technology: JPMJER1901 (Japan)
- Japan Science and Technology: JPMJCR24T3 (Japan)
- Japan Agency for Medical Research and Development (AMED): JP25ama121009 (Japan)
- Japan Agency for Medical Research and Development (AMED): JP25ama121002 (Japan)