EMD-64050

Single-particle
2.88 Å
EMD-64050
3D View Gallery
Deposition: 05/04/2025
Map released: 29/10/2025
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-64050
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ucp summary report (pdf.gz) Map and 9ucp FULL report (pdf.gz)
EMICSS annotations (xml)

cryo-EM structure of M1 muscarinic acetylcholine receptor-alpha5 helix of G11 protein complex bound to iperoxo and nanobody Nb1B4

EMD-64050

Single-particle
2.88 Å
EMD-64050
3D View Gallery
Deposition: 05/04/2025
Map released: 29/10/2025
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Vicugna pacos
Sample: cryo-EM structure of M1 muscarinic acetylcholine receptor-alpha5 helix of G11 protein complex bound to iperoxo and nanobody Nb1B4/de novo design fusion protein
Fitted models: 9ucp

Deposition Authors: Zhang X , Gao K , Liu X
Extracellular nanobody screening using conformationally stable GPCR variants.
Zhang X , Gao K , Nie J, Meng H, Sun X, Zhao J, Liu X
(2025) PNAS , 122 , e2508879122 - e2508879122
PUBMED: 41187083
DOI: doi:10.1073/pnas.2508879122
ISSN: 1091-6490
ASTM: PNASA6