EMD-63121

Single-particle
3.1 Å
EMD-63121
3D View Gallery
Deposition: 14/01/2025
Map released: 21/01/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-63121

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9lir summary report (pdf.gz) Map-9lir FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM Structures Uncover the Unexpected Hinges of IscB for Enhanced Gene Editing

EMD-63121

Single-particle
3.1 Å
EMD-63121
3D View Gallery
Deposition: 14/01/2025
Map released: 21/01/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct
Sample: The ternary complex formed by IscB, wRNA, and Target DNA
Fitted models: 9lir

Deposition Authors: Hu CY, Wang FZ, Ma SS, Zhang SF
Structural insight into IscB's RNA-lid-based inactivation mechanism.
Wang F, Guo R, Zhang S, Cui Y , Wang J, Hu T, Liu K, Wang Q, Liu Y, Nam KH, Zhao ZW , Ji Q, Xu X, Wang E, Zhu Y, Yang Y, Luo M, Ma P , Ma S , Xu C , Hu C
(2026) Nat Struct Mol Biol , 33 , 603 - 614
PUBMED: 41882346
DOI: doi:10.1038/s41594-026-01761-3
ISSN: 1545-9985
Grant Support: