EMD-62842

Single-particle
2.9 Å
EMD-62842
3D View Gallery
Deposition: 23/12/2024
Map released: 12/03/2025
Last modified: 16/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62842

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9l5s summary report (pdf.gz) Map-9l5s FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the thermophile spliceosome (state B*Q1)

EMD-62842

Single-particle
2.9 Å
EMD-62842
3D View Gallery
Deposition: 23/12/2024
Map released: 12/03/2025
Last modified: 16/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
Sample: Spliceosome in state B*Q1
Fitted models: 9l5s

Deposition Authors: Li Y , Fischer P, Wang M, Yuan R, Meng W, Luehrmann R, Lau B , Hurt E , Cheng J
Structural insights into spliceosome fidelity: DHX35-GPATCH1- mediated rejection of aberrant splicing substrates.
Li Y , Fischer P, Wang M, Zhou Q, Song A , Yuan R, Meng W, Chen FX , Luhrmann R, Lau B , Hurt E , Cheng J
(2025) Cell Res , 35 , 296 - 308
PUBMED: 40016598
DOI: doi:10.1038/s41422-025-01084-w
ISSN: 1001-0602
Grant Support: