EMD-62559

Single-particle
2.73 Å
EMD-62559
3D View Gallery
Deposition: 02/12/2024
Map released: 10/12/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62559

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9kt8 summary report (pdf.gz) Map-9kt8 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of HCA2-Gi complex with acifran

EMD-62559

Single-particle
2.73 Å
EMD-62559
3D View Gallery
Deposition: 02/12/2024
Map released: 10/12/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure of HCA2-Gi complex with acifran
Fitted models: 9kt8

Deposition Authors: Wu S
Insights into the Activation Mechanism of HCA1, HCA2, and HCA3.
Wang J, Qian Y, Han Z, Wang Y, Liu Y, Li J, Duanmu Q, Ye S , Qiao A, Wu S
(2025) J Med Chem , 68 , 4527 - 4539
PUBMED: 39936872
DOI: doi:10.1021/acs.jmedchem.4c02567
ISSN: 0022-2623
ASTM: JMCMAR