EMD-62454

Single-particle
3.3 Å
EMD-62454
3D View Gallery
Deposition: 18/11/2024
Map released: 03/12/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62454

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9kn6 summary report (pdf.gz) Map-9kn6 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the HCV IRES-dependent pre-48S translation initiation complex with eIF1A, eIF5B, and eIF3

EMD-62454

Single-particle
3.3 Å
EMD-62454
3D View Gallery
Deposition: 18/11/2024
Map released: 03/12/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Hepacivirus hominis
Sample: HCV IRES-dependent pre-48S translation initiation complex with eIF1A, eIF5B, and eIF3
Fitted models: 9kn6

Deposition Authors: Iwasaki W , Kashiwagi K , Sakamoto A , Nishimoto M, Takahashi M, Machida K , Imataka H, Matsumoto A , Shichino Y , Iwasaki S , Imami K, Ito T
Structural insights into the role of eIF3 in translation mediated by the HCV IRES.
Iwasaki W , Kashiwagi K , Sakamoto A , Nishimoto M, Takahashi M, Machida K , Imataka H, Matsumoto A , Shichino Y , Iwasaki S , Imami K, Ito T
(2025) PNAS , 122 , e2505538122 - e2505538122
PUBMED: 41337487
DOI: doi:10.1073/pnas.2505538122
ISSN: 1091-6490
ASTM: PNASA6