EMD-62281

Single-particle
2.46 Å
EMD-62281
3D View Gallery
Deposition: 03/11/2024
Map released: 19/11/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62281
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9kdm summary report (pdf.gz) Map and 9kdm FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of LIPID-mediated human norepinephrine transporter NET in the presence of Levomilnacipran in an inward-open state at resolution of 2.46 angstrom.

EMD-62281

Single-particle
2.46 Å
EMD-62281
3D View Gallery
Deposition: 03/11/2024
Map released: 19/11/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Sodium-dependent noradrenaline transporter
Fitted models: 9kdm

Deposition Authors: Zhang H, Jiang Y, Xu EH
Unveiling conformation-selective regulation of the norepinephrine transporter.
Zhang H, Zhang T, Wang D, Dai A, Mao J, Chen Q, Du T, Lu X, Hao Y, Zhang C, Yin YL, Hu W, Pan B, Jin S, Jiang M, Si Y, Yuan Q, Wang MW, Zheng M, Wang Z, Yang D, Xu HE, Jiang Y
(2025) Cell , 188 , 6861
PUBMED: 41138730
DOI: doi:10.1016/j.cell.2025.10.002
ISSN: 1097-4172