EMD-62135

Single-particle
2.8 Å
EMD-62135
3D View Gallery
Deposition: 22/10/2024
Map released: 25/06/2025
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62135

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9k6t summary report (pdf.gz) Map-9k6t FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM Structure of hAGO2D669A-siRNA-target (21-nt)

EMD-62135

Single-particle
2.8 Å
EMD-62135
3D View Gallery
Deposition: 22/10/2024
Map released: 25/06/2025
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of hAGO2D669A-siRNA-target (21-nt)
Fitted models: 9k6t

Deposition Authors: Li ZZ, Xu QK, Wu JP, Shen EZ
Mechanistic insights into RNA cleavage by human Argonaute2-siRNA complex.
Li Z, Xu Q, Zhang Y , Zhong J , Zhang T, Xue J, Liu S, Gao H , Zhang ZZZ, Wu J , Shen EZ
(2025) Cell Res , 35 , 453 - 464
PUBMED: 40240484
DOI: doi:10.1038/s41422-025-01114-7
ISSN: 1001-0602
Grant Support: