EMD-62028

Single-particle
3.15 Å
EMD-62028
3D View Gallery
Deposition: 20/10/2024
Map released: 15/10/2025
Last modified: 31/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62028

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9k3t summary report (pdf.gz) Map-9k3t FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of TMPRSS2 in complex with Fab fragments of 752 mAb and 2228 mAb

EMD-62028

Single-particle
3.15 Å
EMD-62028
3D View Gallery
Deposition: 20/10/2024
Map released: 15/10/2025
Last modified: 31/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: TMPRSS2 ECD and Fab fragments complex
Fitted models: 9k3t

Deposition Authors: Katsura K, Hisano T, Matsumoto T, Shirouzu M
Monoclonal antibodies against human TMPRSS2 prevent infection by any SARS-CoV-2 variant.
Harada M, Matsumoto T, Yamamoto M, Goda J, Idei A, Ohtaki K, Kojima N, Yoneda N, Miyauchi K, Katsura K, Ikeda M, Hanada K, Ishizuka-Katsura Y, Hosaka T, Hisano T, Kaizuka T, Yamamoto T, Matsuda M, Nakayama M, Sugimoto-Ishige A, Sakuma M, Hashimoto R, Takayama K, Nakayama M, Nguyen CT, Ishigaki H, Itoh Y, Hashizume Y, Yoshida M, Kawaguchi Y, Takeda M, Koseki H, Shirouzu M, Inoue JI, Saito T
(2025) iScience , 28 , 113424 - 113424
PUBMED: 41393976
DOI: doi:10.1016/j.isci.2025.113424
ISSN: 2589-0042