EMD-61868
Cryo-EM structure of one subunit of the human XPR1 homodimer with both the intracellular and extracellular gates in an open state, obtained through local refinement
EMD-61868
Single-particle3.48 Å
Deposition: 11/10/2024Map released: 27/08/2025
Last modified: 17/09/2025
Sample Organism:
Homo sapiens
Sample: Homodimer of XPR1
Fitted models: 9jxm
Deposition Authors: Wang X, Bai Z, Wallis C
,
Wang H,
Han Y,
Jin R,
Lei M
,
Gu C,
Jessen H
,
Shears S,
Sun Y,
Corry B
,
Zhang Y
Sample: Homodimer of XPR1
Fitted models: 9jxm
Deposition Authors: Wang X, Bai Z, Wallis C
,
Wang H,
Han Y,
Jin R,
Lei M
,
Gu C,
Jessen H
,
Shears S,
Sun Y,
Corry B
,
Zhang Y
KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1.
Wang X,
Bai Z,
Wallis C
,
Wang H,
Han Y,
Jin R,
Lei M
,
Yang T,
Gu C,
Jessen H
,
Shears S,
Sun Y,
Corry B
,
Zhang Y
(2025) Mol Cell , 85 , 3209 - 3224.e8
,
Wang H,
Han Y,
Jin R,
Lei M
,
Yang T,
Gu C,
Jessen H
,
Shears S,
Sun Y,
Corry B
,
Zhang Y
(2025) Mol Cell , 85 , 3209 - 3224.e8
Grant Support:
