EMD-61864
Cryo-EM structure of human XPR1 with InsP8 in an 'arch-like' intermediate state of the SPX domain
EMD-61864
Single-particle3.31 Å
Deposition: 11/10/2024Map released: 27/08/2025
Last modified: 17/09/2025
Sample Organism:
Homo sapiens
Sample: Homodimer of XPR1
Fitted models: 9jxi
Deposition Authors: Wang X, Bai Z, Wallis C
,
Wang H,
Han Y,
Jin R,
Lei M ,
Gu C,
Jessen H ,
Shears S,
Sun Y,
Corry B ,
Zhang Y
Sample: Homodimer of XPR1
Fitted models: 9jxi
Deposition Authors: Wang X, Bai Z, Wallis C
,
Wang H,
Han Y,
Jin R,
Lei M ,
Gu C,
Jessen H ,
Shears S,
Sun Y,
Corry B ,
Zhang Y
KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1.
Wang X,
Bai Z,
Wallis C ,
Wang H,
Han Y,
Jin R,
Lei M ,
Yang T,
Gu C,
Jessen H ,
Shears S,
Sun Y,
Corry B ,
Zhang Y
(2025) Mol Cell , 85 , 3209 - 3224.e8
,
Wang H,
Han Y,
Jin R,
Lei M ,
Yang T,
Gu C,
Jessen H ,
Shears S,
Sun Y,
Corry B ,
Zhang Y
(2025) Mol Cell , 85 , 3209 - 3224.e8
Grant Support: