EMD-61113

Single-particle
2.9 Å
EMD-61113
3D View Gallery
Deposition: 08/08/2024
Map released: 23/04/2025
Last modified: 23/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-61113

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9j3c summary report (pdf.gz) Map-9j3c FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of NAT10 with Co-enzyme A

EMD-61113

Single-particle
2.9 Å
EMD-61113
3D View Gallery
Deposition: 08/08/2024
Map released: 23/04/2025
Last modified: 23/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: NAT10 with Co-enzyme A
Fitted models: 9j3c

Deposition Authors: Jiang Y, Xia J
Targeting NAT10 attenuates homologous recombination via destabilizing DNA:RNA hybrids and overcomes PARP inhibitor resistance in cancers.
Xu Z, Zhu M, Geng L, Zhang J , Xia J, Wang Q , An H, Xia A, Yu Y, Liu S, Tong J, Zhu WG, Jiang Y, Sun B
(2025) Drug Resist Updat. , 81 , 101241 - 101241
PUBMED: 40132530
DOI: doi:10.1016/j.drup.2025.101241
ISSN: 1532-2084
Grant Support: