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EMD-61058
Paused elongation complex of mammalian RNA polymerase II with nucleosome (PEC2-nuc)
EMD-61058
Single-particle3.4 Å
Deposition: 02/08/2024Map released: 05/02/2025
Last modified: 18/06/2025
Sample Organism:
Homo sapiens,
Sus scrofa
Sample: RNA polymerase II in complex with DSIF, NELF, and nucleosome
Fitted models: 9j0n
Deposition Authors: Naganuma M
,
Kujirai T ,
Ehara H ,
Uejima T ,
Ito T ,
Goto M ,
Aoki M,
Henmi M ,
Miyamoto-Kohno S,
Shirouzu M ,
Kurumizaka H ,
Sekine S
Sample: RNA polymerase II in complex with DSIF, NELF, and nucleosome
Fitted models: 9j0n
Deposition Authors: Naganuma M
,
Kujirai T ,
Ehara H ,
Uejima T ,
Ito T ,
Goto M ,
Aoki M,
Henmi M ,
Miyamoto-Kohno S,
Shirouzu M ,
Kurumizaka H ,
Sekine S
Structural insights into promoter-proximal pausing of RNA polymerase II at +1 nucleosome.
Naganuma M ,
Kujirai T ,
Ehara H ,
Uejima T ,
Ito T ,
Goto M ,
Aoki M,
Henmi M ,
Miyamoto-Kohno S,
Shirouzu M ,
Kurumizaka H ,
Sekine SI
(2025) Sci Adv , 11 , eadu0577 - eadu0577
,
Kujirai T ,
Ehara H ,
Uejima T ,
Ito T ,
Goto M ,
Aoki M,
Henmi M ,
Miyamoto-Kohno S,
Shirouzu M ,
Kurumizaka H ,
Sekine SI
(2025) Sci Adv , 11 , eadu0577 - eadu0577
Grant Support:
- Japan Society for the Promotion of Science (JSPS): JP20H05690 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP20H03201 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP23H05475 (Japan)
- Japan Society for the Promotion of Science (JSPS): JPMJER1901 (Japan)
- Japan Agency for Medical Research and Development (AMED): JP23ama121009 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP24H00062 (Japan)
- Other private: (Japan)
- Japan Society for the Promotion of Science (JSPS): JP22K15033 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP23K17392 (Japan)