EMD-60982

Single-particle
3.2 Å
EMD-60982
3D View Gallery
Deposition: 29/07/2024
Map released: 19/03/2025
Last modified: 13/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-60982

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ixz summary report (pdf.gz) Map-9ixz FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

human KCNQ2-CaM-Ebio3 Complex in the Presence of PIP2

EMD-60982

Single-particle
3.2 Å
EMD-60982
3D View Gallery
Deposition: 29/07/2024
Map released: 19/03/2025
Last modified: 13/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human KCNQ2-CaM-Ebio3 complex
Fitted models: 9ixz

Deposition Authors: Yang Z, Guo J
Small molecule inhibits KCNQ channels with a non-blocking mechanism.
Li J, Yang Z, Zhang S, Ye Y, He J, Zhang Y, Han H, Kong W, Liu J, Min Y, Shen J, Mei L, Chen Z, Hou P, Guo J , Zhang Q , Yang H
(2025) Nat Chem Biol , 21 , 1100 - 1109
PUBMED: 39814994
DOI: doi:10.1038/s41589-024-01834-8
ISSN: 1552-4469