EMD-60797

Single-particle
3.37 Å
EMD-60797
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Deposition: 13/07/2024
Map released: 28/05/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-60797
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9iqx summary report (pdf.gz) Map and 9iqx FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the human TRPV4-RhoA in complex with AH001

EMD-60797

Single-particle
3.37 Å
EMD-60797
3D View Gallery
Deposition: 13/07/2024
Map released: 28/05/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure of the human TRPV4-RhoA in complex with AH001
Fitted models: 9iqx

Deposition Authors: Yuan Z , Ruan SS, Li SL
Inactivation of RhoA for Hypertension Treatment Through the TRPV4-RhoA-RhoGDI1 Axis.
Wang J , Yuan Z , Yu N, Jiao Q, Zhou H, Liao W, Shan J, Ruan S, Zhao Y , Mo Y, Qi L, Li T, Fu J, Ke B , Xu Y , Qian X , Zhang J , Zhao Z, Li S, Wang R, Li H
(2025) Circulation , 152 , 519 - 536
PUBMED: 40518994
DOI: doi:10.1161/CIRCULATIONAHA.124.071884
ISSN: 1524-4539