EMD-60348

Single-particle
3.01 Å
EMD-60348
3D View Gallery
Deposition: 30/05/2024
Map released: 26/02/2025
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-60348
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8zpl summary report (pdf.gz) Map and 8zpl FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM strucutre of CXCR4 complexed with antagonist HF51116

EMD-60348

Single-particle
3.01 Å
EMD-60348
3D View Gallery
Deposition: 30/05/2024
Map released: 26/02/2025
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: HF51116-CXCR4-KOR-Nb6
Fitted models: 8zpl

Deposition Authors: Jiao HZ, Hu HL
Structural mechanisms underlying the modulation of CXCR4 by diverse small-molecule antagonists.
Sang X , Jiao H, Meng Q, Fang X, Pan Q, Zhou J, Qian T, Zhang W, Xu Y , An J, Huang Z, Hu H
(2025) PNAS , 122 , e2425795122 - e2425795122
PUBMED: 40063796
DOI: doi:10.1073/pnas.2425795122
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: