EMD-60325

Single-particle
2.4 Å
EMD-60325 Deposition: 29/05/2024
Map released: 11/09/2024
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-60325

Cryo-EM structure of human norepinephrine transporter NET bound with atomoxetine in an outward-open state at a resolution of 2.4 angstrom

EMD-60325

Single-particle
2.4 Å
EMD-60325 Deposition: 29/05/2024
Map released: 11/09/2024
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: human norepinephrine transporter NET in complex with Nb_BB4
Fitted models: 8zp2

Deposition Authors: Song AL, Wu XD
Mechanistic insights of substrate transport and inhibitor binding revealed by high-resolution structures of human norepinephrine transporter.
Song A, Wu X
(2024) Cell Res , 34 , 810 - 813
PUBMED: 39223283
DOI: doi:10.1038/s41422-024-01024-0
ISSN: 1001-0602
Grant Support: