EMD-57339

Single-particle
7.5 Å
EMD-57339
3D View Gallery
Deposition: 01/04/2026
Map released: 22/07/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-57339

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-29rt summary report (pdf.gz) Map-29rt FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Insulin receptor ecto-domain in inverted-U apo-conformation

EMD-57339

Single-particle
7.5 Å
EMD-57339
3D View Gallery
Deposition: 01/04/2026
Map released: 22/07/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: insulin receptor ecto-domain in inverted-U apo-conformation
Fitted models: 29rt

Deposition Authors: Polak M, Novacek J, Jiracek J

Antagonistic insulin mimetics lock the insulin receptor in an alternative apo-state
Polak M, Pinkas M
To Be Published