EMD-56898

Single-particle
2.7 Å
EMD-56898
3D View Gallery
Deposition: 23/02/2026
Map released: 13/05/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-56898

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-28vy summary report (pdf.gz) Map-28vy FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

sCMGE assembled on ARS1 DNA with Sld2 and RPA

EMD-56898

Single-particle
2.7 Å
EMD-56898
3D View Gallery
Deposition: 23/02/2026
Map released: 13/05/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae, synthetic construct
Sample: Single CMGE complex with RPA on replication origin
Fitted models: 28vy

Deposition Authors: Palm G , Costa A
Structure of the pre-initiation complex explains CMGE biogenesis.
Puhringer T, Canal B, Palm G , Butryn A, Couves EC, Willhoft O, Lewis JS, Diffley JFX, Costa A
(2026) Nature , 655 , 1330 - 1338
PUBMED: 42310460
DOI: doi:10.1038/s41586-026-10657-7
ISSN: 1476-4687
ASTM: NATUAS