EMD-56538

Single-particle
2.83 Å
EMD-56538
3D View Gallery
Deposition: 02/02/2026
Map released: 19/08/2026
Last modified: 19/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-56538

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-28iz summary report (pdf.gz) Map-28iz FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the human two pore domain potassium ion channel TASK-3 L122V mutant (K2P9.1)

EMD-56538

Single-particle
2.83 Å
EMD-56538
3D View Gallery
Deposition: 02/02/2026
Map released: 19/08/2026
Last modified: 19/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: K2P9.1 L122V homodimer
Fitted models: 28iz

Deposition Authors: Hall PR, Rodstrom KEJ, Tucker SJ
Equivalent gain-of-function variants in KCNK3 and KCNK9 and their contribution to distinct TASK K2P channelopathies.
Crowther KM, Jouen-Tachoire TRH, Proks P, Hall PR, Veale EL, Sormann J, Rodstrom KEJ, Muller T, Wortmann SB, Barisic N, Hauser N, Salpietro V, Forsyth R, Williams L, Derrabi N, Bacino CA, Rosenfeld JA, Houlden H, Newstead S, Wright CF, Fasham J, Mathie AA, Maroofian R, Tucker SJ
(2026) J Gen Physiol , 158
PUBMED: 42560358
DOI: doi:10.1085/jgp.202613989
ISSN: 1540-7748