EMD-56238

Subtomogram averaging
18.74 Å
EMD-56238
3D View Gallery
Deposition: 07/01/2026
Map released: 18/02/2026
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-56238

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

In situ cryo-ET subtomogram averaged map of Flotillin complex

EMD-56238

Subtomogram averaging
18.74 Å
EMD-56238
3D View Gallery
Deposition: 07/01/2026
Map released: 18/02/2026
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Flotillin complex in HeLa TMEM192-3xHA cells using in situ cryo-ET

Deposition Authors: Li D , Lizarrondo J , Wilfling F
Cathepsin-dependent amyloid formation drives mechanical rupture of lysosomal membranes.
Li D , Zhang W , Medina M , Stuke JFM , Schwarz A , Brill J, Brenner J , Kraus F , Ohlerich S, Lizarrondo J , Pflaum J , Grass JH , Soltow LM, Hammerschmid D , Weber N, Welsch S , Langer JD, Windbergs M , Harper JW , Schuman E, Hummer G , Grotjahn DA , Wilfling F
(2026) bioRxiv
PUBMED: 41648416
DOI: doi:10.64898/2026.01.17.700056
ISSN: 2692-8205
Grant Support: