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EMD-56238

Subtomogram averaging
18.74 Å
EMD-56238
3D View Gallery
Deposition: 07/01/2026
Map released: 18/02/2026
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-56238
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

In situ cryo-ET subtomogram averaged map of Flotillin complex

EMD-56238

Subtomogram averaging
18.74 Å
EMD-56238
3D View Gallery
Deposition: 07/01/2026
Map released: 18/02/2026
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Flotillin complex in HeLa TMEM192-3xHA cells using in situ cryo-ET

Deposition Authors: Li D , Lizarrondo J , Wilfling F
Cathepsin-dependent amyloid formation drives mechanical rupture of lysosomal membranes.
Li D , Zhang W, Medina M, Stuke JFM, Schwarz A, Brill J, Brenner J, Kraus F, Ohlerich S, Lizarrondo J , Pflaum J, Grass JH, Soltow LM, Hammerschmid D, Weber N, Welsch S, Langer JD, Windbergs M, Harper JW, Schuman E, Hummer G, Grotjahn DA, Wilfling F
(2026) bioRxiv
PUBMED: 41648416
DOI: doi:10.64898/2026.01.17.700056
ISSN: 2692-8205
Grant Support:
  • Aligning Science Across Parkinsons (ASAP): (United States)
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