EMD-55655

Single-particle
3.5 Å
EMD-55655
3D View Gallery
Deposition: 11/11/2025
Map released: 20/05/2026
Last modified: 20/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-55655

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Focused map of CUL2-LRRC58-EloC interface region from LRRC58- EloB/C-CDO1 in complex with neddylated CUL2-RBX1-ARIH1-Ub

EMD-55655

Single-particle
3.5 Å
EMD-55655
3D View Gallery
Deposition: 11/11/2025
Map released: 20/05/2026
Last modified: 20/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: LRRC58-EloB/C-CDO1 in complex with neddylated CUL2-RBX1-ARIH1-Ub

Deposition Authors: Stier L , Andree GA , Schulman BA
Cysteine availability tunes ubiquitin signaling via inverse stability of LRRC58 E3 ligase and its substrate CDO1.
Andree GA , Stier LJ, Schmiederer K, Thielen AS, Schmid L, Maiwald SA, Gottemukkala KV, Du J, von Gronau S, Strasser C, Muller J, Henneberg LT, Guyot C, Kleiger G, Mann M, Murray PJ, Schulman BA
(2026) Nat Commun , 17
PUBMED: 42098103
DOI: doi:10.1038/s41467-026-72524-3
ISSN: 2041-1723
Grant Support: