EMD-55651

Single-particle
3.03 Å
EMD-55651
3D View Gallery
Deposition: 11/11/2025
Map released: 09/09/2026
Last modified: 09/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-55651

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9t7q summary report (pdf.gz) Map-9t7q FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of EA-Ri-112-bound D3 dopamine receptor with mini-Go

EMD-55651

Single-particle
3.03 Å
EMD-55651
3D View Gallery
Deposition: 11/11/2025
Map released: 09/09/2026
Last modified: 09/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: GPCR-Go protein complex
Fitted models: 9t7q

Deposition Authors: Yardeni EH , Kiss DJ , Keseru GM , Shalev-Benami M
The structure of the dopamine D3 receptor bound to cariprazine reveals principles for partial agonists with designed pharmacology
Hadas Yardeni E, Kiss DJ , Sanchez J, Shavit K, Szepesi Kovacs D, Egyed A, Vogt CD, Gaitonde SA, Glenn J, Canals M, Bouvier M, Newman AH, Lane JR, Keseru GM , Shalev-Benami M
(2026) Sci Adv , 12
DOI: doi:10.1126/sciadv.aef7411
ISSN: 2375-2548
Grant Support: