EMD-55521

Single-particle
3.44 Å
EMD-55521
3D View Gallery
Deposition: 30/10/2025
Map released: 25/03/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-55521

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9t3y summary report (pdf.gz) Map-9t3y FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of alphaM/beta2:C3d-anti-CR3-Nb headpiece complex (HPO2 3D class reconstruction)

EMD-55521

Single-particle
3.44 Å
EMD-55521
3D View Gallery
Deposition: 30/10/2025
Map released: 25/03/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Complement C3d-alphaM/beta2 headpiece complex (wt HPO2)
Fitted models: 9t3y

Deposition Authors: Andersen GR , Fruergaard MU
Three cryo-EM structures of complement C3d-bound alpha M beta 2 reveal an unexpected layer of dynamics for alpha I-containing integrin receptors.
Lorentzen J, Fruergaard MU , Lukacsi S, Jorgensen MH, van Veghel TLG, Jensen RK, Pietrzak-Lichwa KJ, Bajtay Z, Horejsi V, Flygaard RK, Vorselen D, Mortensen SA, Andersen GR
(2026) Sci Adv , 12 , eaea7241 - eaea7241
PUBMED: 42102216
DOI: doi:10.1126/sciadv.aea7241
ISSN: 2375-2548
Grant Support: