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EMD-55484

Single-particle
2.78 Å
EMD-55484
3D View Gallery
Deposition: 24/10/2025
Map released: 09/09/2026
Last modified: 09/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-55484

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 | Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9t35 summary report (pdf.gz) Map-9t35 FULL report (pdf.gz)

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VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of homo-hexameric hLRRC8A L402W

EMD-55484

Single-particle
2.78 Å
EMD-55484
3D View Gallery
Deposition: 24/10/2025
Map released: 09/09/2026
Last modified: 09/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: the homo-hexamer hLRRC8A L402W
Fitted models: 9t35

Deposition Authors: Bertelli S, Wang L, Klussendorf M, Pusch M, Dutzler R, Stauber T
The intracellular subdomain of the volume regulated anion channel subunit LRRC8A is a hotspot of channel activation
Bertelli S, Wang L, Klussendorf M, Pusch M, Dutzler R, Stauber T
(2026) To Be Published
DOI: doi:10.1038/s41467-026-77507-y
Grant Support:
  • Swiss National Science Foundation: 10.006.508 (Switzerland)
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