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EMD-55409
HIV-1 integrase filament at the luminal side of capsid lattice by subtomogram averaging.
EMD-55409
Subtomogram averaging12.56 Å
Deposition: 20/10/2025Map released: 10/12/2025
Last modified: 10/12/2025
Sample Organism:
Human immunodeficiency virus 1
Sample: Human immunodeficiency virus 1
Deposition Authors: Cherepanov P
,
Chenavier F ,
Hope J ,
Nans A ,
Zhang P
Sample: Human immunodeficiency virus 1
Deposition Authors: Cherepanov P
,
Chenavier F ,
Hope J ,
Nans A ,
Zhang P
Structural bases for integrase-RNA binding and retention of viral RNA within HIV-1 capsid cores
Singer M,
Li Z,
Rey SJ,
Hope J ,
Cook JN,
Punch E,
Smith J,
Zhou Z,
Maslen S,
Masino L,
Nans A ,
Skehel M,
Taylor AI,
Zhang P ,
Perilla JR,
Engelman NA,
Cherepanov P
To Be Published
,
Cook JN,
Punch E,
Smith J,
Zhou Z,
Maslen S,
Masino L,
Nans A ,
Skehel M,
Taylor AI,
Zhang P ,
Perilla JR,
Engelman NA,
Cherepanov P
To Be Published
Grant Support:
- Medical Research Council (MRC, United Kingdom): CC2058 (United Kingdom)
- Wellcome Trust: CC2058 (United Kingdom)
- Cancer Research UK: CC2058 (United Kingdom)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): U54AI170791 (United States)