EMD-54949

Single-particle
3.06 Å
EMD-54949
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Deposition: 31/08/2025
Map released: 04/02/2026
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54949
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EMICSS annotations (xml)

Type I-F_HNH variant Cascade RNP bound to dsDNA with trace of target strand into HNH domain rotated in middle position

EMD-54949

Single-particle
3.06 Å
EMD-54949
3D View Gallery
Deposition: 31/08/2025
Map released: 04/02/2026
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Selenomonas sp.
Sample: Type I-F_HNH effector complex bound to dsDNA

Deposition Authors: Fuglsang A, Montoya G
Conformational dynamics of CRISPR-Cas type I-F-HNH inform nickase engineering in a cascade scaffold.
Fuglsang A, Rout SS, Koutna EB , Sofos N, Gallego AR, Montoya G
(2026) Nucleic Acids Res , 54
PUBMED: 41603736
DOI: doi:10.1093/nar/gkag053
ISSN: 1362-4962
ASTM: NARHAD
Grant Support: