EMD-54891

Single-particle
2.49 Å
EMD-54891
3D View Gallery
Deposition: 25/08/2025
Map released: 29/07/2026
Last modified: 29/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54891

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Focussed map of ternary PROTAC-mediated complex consisting of Cereblon, DDB1 and BRD4-BD1, non-covalently linked by JQ1-AcN

EMD-54891

Single-particle
2.49 Å
EMD-54891
3D View Gallery
Deposition: 25/08/2025
Map released: 29/07/2026
Last modified: 29/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ternary PROTAC-mediated complex consisting of Cereblon, DDB1 and BRD4-BD1, non-covalently linked by JQ1-AcN

Deposition Authors: Fischer G, Peter D, Arce-Solano S, Kessler D
Enzyme-Activated Sugar-Coated Bifunctional Degraders.
Zhu Q, Fischer G, Cheng SS, Payne NC, Peter D, Mody AC, Arce-Solano S, Shen D, Lin Z, Mazitschek R, Kessler D, Woo CM
(2025) J Am Chem Soc , 147 , 34672 - 34680
PUBMED: 40937862
DOI: doi:10.1021/jacs.5c09843
ISSN: 1520-5126
ASTM: JACSAT
Grant Support: