EMD-54623

Single-particle
4.12 Å
EMD-54623
3D View Gallery
Deposition: 31/07/2025
Map released: 08/07/2026
Last modified: 14/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54623

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9s67 summary report (pdf.gz) Map-9s67 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of WIV1 spike monomer in complex with neutralizing antibody VA14_26

EMD-54623

Single-particle
4.12 Å
EMD-54623
3D View Gallery
Deposition: 31/07/2025
Map released: 08/07/2026
Last modified: 14/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Bat SARS-like coronavirus WIV1, Homo sapiens
Sample: Antibody-antigen complex between VA14_26 antibody FAB and Bat SARS-like coronavirus WIV1 Spike glycoprotein
Fitted models: 9s67

Deposition Authors: Upadhyay A, Alguel Y, Cherepanov P
Targeting of conserved spike epitopes enables broad antibody neutralisation of diverse bat sarbecoviruses.
Upadhyay A, Seow J, Alguel Y, Newman J, Thakur N, Hay AL, Tam JCH, Nans A, Orton RJ, Bailey D, Cherepanov P, Doores KJ
(2026) PLoS Biol , 24 , e3003882 - e3003882
PUBMED: 42821509
DOI: doi:10.1371/journal.pbio.3003882
ISSN: 1545-7885
Grant Support: