EMD-54540

Single-particle
2.31 Å
EMD-54540
3D View Gallery
Deposition: 24/07/2025
Map released: 24/06/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54540
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9s3m summary report (pdf.gz) Map and 9s3m FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of Gephyrin E domain in complex with Darpin 27F3

EMD-54540

Single-particle
2.31 Å
EMD-54540
3D View Gallery
Deposition: 24/07/2025
Map released: 24/06/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus, synthetic construct
Sample: Gephyrin in complex with Darpin 27F3 partner
Fitted models: 9s3m

Deposition Authors: Ortiz-Lopez D, Hove T, Boettcher B, Schindelin H
Cryo-EM structures of higher order Gephyrin oligomers reveal principles of inhibitory postsynaptic scaffold organization.
Ortiz-Lopez D, Hove TT, Huhn C, Camuso S, van Gen Hassend PM, Sander B, Campbell BFN, Tyagarajan SK, Pluckthun A, Specht CG, Maric HM, Bottcher B, Schindelin H
(2026) Nat Commun , 17
PUBMED: 41991925
DOI: doi:10.1038/s41467-026-71771-8
ISSN: 2041-1723