EMD-54349

Single-particle
3.1 Å
EMD-54349
3D View Gallery
Deposition: 10/07/2025
Map released: 18/03/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54349
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

Map B Locally refined interactions of ZSWIM8-CUL3 complex bound to AGO2-miR-7-CYRANO

EMD-54349

Single-particle
3.1 Å
EMD-54349
3D View Gallery
Deposition: 10/07/2025
Map released: 18/03/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: CYRANO-AGO2-miR-7 in complex with ZSWIM8-ELONGIN B/C, CUL3

Deposition Authors: Farnung J , Slobodyanyuk E , Bartel DP , Schulman BA
The E3 ubiquitin ligase mechanism specifying targeted microRNA degradation.
Farnung J , Slobodyanyuk E , Wang PY , Blodgett LW , Lin DH , von Gronau S, Schulman BA , Bartel DP
(2026) Nature , 652 , 784 - 793
PUBMED: 41851464
DOI: doi:10.1038/s41586-026-10232-0
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: