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EMD-54253
Structure of 70S ribosome-EF-G(P610L)-GDP-Pi-apramycin complex with tRNAs in hybrid state 1 (H1- EF-G(P610L)-GDP-Pi)
EMD-54253
Single-particle3.0 Å
Deposition: 03/07/2025Map released: 01/10/2025
Last modified: 12/11/2025
Sample Organism:
Escherichia coli K-12
Sample: E. coli ribosome complex 70S-Apr-EF-G(P610L)-GDP-Pi-fMet-Phe-tRNAPhe-tRNA-fMet-mRNA
Fitted models: 9rtu
Deposition Authors: Ghosh Dastidar N
,
Freyer N,
Petrychenko V ,
Schwarzer AC,
Peng BZ ,
Samatova E,
Kothe C,
Schmidt M,
Peske F,
Politi A,
Urlaub H ,
Fischer N ,
Rodnina MV ,
Wohlgemuth I
Sample: E. coli ribosome complex 70S-Apr-EF-G(P610L)-GDP-Pi-fMet-Phe-tRNAPhe-tRNA-fMet-mRNA
Fitted models: 9rtu
Deposition Authors: Ghosh Dastidar N
,
Freyer N,
Petrychenko V ,
Schwarzer AC,
Peng BZ ,
Samatova E,
Kothe C,
Schmidt M,
Peske F,
Politi A,
Urlaub H ,
Fischer N ,
Rodnina MV ,
Wohlgemuth I
Selective silencing of antibiotic-tethered ribosomes as a resistance mechanism against aminoglycosides.
Ghosh Dastidar N ,
Freyer NS ,
Petrychenko V ,
de A P Schwarzer AC ,
Peng BZ ,
Samatova E,
Kothe C,
Schmidt M,
Peske F,
Politi AZ,
Urlaub H ,
Fischer N ,
Rodnina MV ,
Wohlgemuth I
(2025) Nat Commun , 16 , 9568 - 9568
,
Freyer NS ,
Petrychenko V ,
de A P Schwarzer AC ,
Peng BZ ,
Samatova E,
Kothe C,
Schmidt M,
Peske F,
Politi AZ,
Urlaub H ,
Fischer N ,
Rodnina MV ,
Wohlgemuth I
(2025) Nat Commun , 16 , 9568 - 9568
Grant Support:
- German Research Foundation (DFG): Leibniz Prize (to M.V.R.) & SFB 860 (Germany)
- Max Planck Society: (Germany)