EMD-54056

Single-particle
4.2 Å
EMD-54056
3D View Gallery
Deposition: 18/06/2025
Map released: 11/02/2026
Last modified: 09/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54056

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9rmc summary report (pdf.gz) Map-9rmc FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL+6 class 1

EMD-54056

Single-particle
4.2 Å
EMD-54056
3D View Gallery
Deposition: 18/06/2025
Map released: 11/02/2026
Last modified: 09/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: BAF in complex with a OCT4/SOX2-bound nucleosome
Fitted models: 9rmc

Deposition Authors: Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare G, Thoma NH
The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4-SOX2.
Weiss J, Vecchia L, Domjan D , Cavadini S, Sabantsev A, Kempf G, Pathare GR, Brackmann K, Michael AK, Kater L, Hietter-Pfeiffer E, Haddawi M, Kuber UP , Muhlhausser S, Grand RS, Stadler MB, Deindl S, Thoma NH
(2026) Mol Cell , 86 , 625 - 639.e8
PUBMED: 41679301
DOI: doi:10.1016/j.molcel.2026.01.021
ISSN: 1097-2765
ASTM: MOCEFL