EMD-54053

Single-particle
3.94 Å
EMD-54053
3D View Gallery
Deposition: 18/06/2025
Map released: 25/03/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54053
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9rma summary report (pdf.gz) Map and 9rma FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of alphaM I-domain:C3d-anti-CR3-Nb complex focused refinement from the alphaM/beta2:C3d-anti-CR3-Nb headpiece complex

EMD-54053

Single-particle
3.94 Å
EMD-54053
3D View Gallery
Deposition: 18/06/2025
Map released: 25/03/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: alphaM I-domain:C3d-anti-CR3-Nb complex
Fitted models: 9rma

Deposition Authors: Fruergaard MU , Andersen GR
Three cryo-EM structures of complement C3d-bound alpha M beta 2 reveal an unexpected layer of dynamics for alpha I-containing integrin receptors.
Lorentzen J, Fruergaard MU , Lukacsi S, Jorgensen MH, van Veghel TLG, Jensen RK, Pietrzak-Lichwa KJ, Bajtay Z, Horejsi V, Flygaard RK, Vorselen D, Mortensen SA, Andersen GR
(2026) Sci Adv , 12 , eaea7241 - eaea7241
PUBMED: 42102216
DOI: doi:10.1126/sciadv.aea7241
ISSN: 2375-2548
Grant Support: